127. What is true about linkage analysis in familial gene disorders: [AIIMS-NOV-2007]
a. Characteristic DNA polymorphism in a family is associated with disorders
b. Characteristic DNA polymorphism WITH A CLINICAL PHENOTYPE
C.Useful to make pedigree chart to show affected and non-affected family members
D.Used to make a pedigree chart to show non-paternity
OPERATION HARRI-PAGE-372-FIG-56-10 (SESSION 26 – 2.9.07)
111. Caspases are involved in: [AIIMS NOV 2007]
a. Apoptosis
b. ..
c. ..
d.
OPERATION HARRI-PAGE-455-FIG-69.1 (SESSION 27 - 9.9.07)
96. Therapeutic monitoring is done for all of the following except: [AIIMS-NOV-2007]
a. Tacrolimus
b. Metformin
c. Cyclosporine
d. Phenytoin
OPERATION HARRI-APPENDIX-TABLE-A5
76. HACEK group includes all except: [AIIMS-NOV-2007]
a. Hemophilus aprophillus
b. Acinetobacter baumanni
c. Eikenella corrodens
d. Cardiobacterium hominis
OPERATION HARRI--P 867 (SESSION 32 – 7.10.07)
79. The medium used for Vibrio cholerae is: [AIIMS-NOV-2007]
a. Thayer-martin
b. TCBS medium
c. Scirrow’s medium
d. Loeffer’s
OPERATION HARRI –P 911 (SESSION 34 – 14.10.07)
(also in consultant’s discussion)
78. Lancefield grouping of streptococci is done by using: [AIIMS-NOV-2007]
a. M protein
b. Group C peptidoglycan cell wall
c. Group C carbohydrate antigen
d. ..
OPERATION HARRI -P-823 (SESSION 32 – 7.10.07)
23. . Not seen in SIADH is: [AIIMS-NOV-2007]
a. Hyponatremia
b. Hypouricemia
c. Volume depletion
d. ..
OPERATION HARRI -P-256 (SESSION 26 – 2.9.07)
(Also in consultant’s discussion)
28. . Bicarbonate is maximally absorbed from: [AIIMS-NOV-2007]
a. PCT
b. DCT
c. Collecting duct
d. Thick ascending loop of Henle
OPERATION HARRI -P-263 (SESSION 26 – 2.9.07)
(also in consultant’s discussion)
81. Regarding respiratory viruses all are true except: [AIIMS-NOV-2007]
a. RSV is the most common cause of bronchiolitis in infants
b. Mumps causes septic meningitis in adults
c. ..
d. ..
OPERATION HARRI -P-1063, 1154 (SESSION 9 – 20.5.07)
83. True about polioviruses is: [AIIMS-NOV-2007]
a. Most cases are symptomatic
b. Inactivated vaccines given I.M. produce spastic paralysis
c. ..
d. Inactivated polio vaccine are given to child less than 3 years of age
OPERATION HARRI -P-1147 (SESSION 9 – 20.5.07)
67. Mirena is: [AIIMS-NOV-2007]
a. Used in abortion
b. Anti-progesterone
c. Progesterone IUCD
d. Hormonal implant
OPERATION HARRI -P-281-TAB, 283 (SESSION 26 – 2.9.07)
107. All of the following can be used for thromboprophylaxis except: [AIIMS-NOV-2007]
a. Heparin
b. Aspirin
c. Warfarin
d. Antithrombin-III
OPERATION HARRI -P-687-689 (SESSION 29 – 23.9.07)
108. Used for the treatment of migraine, the triptans act through: [AIIMS-NOV-2007]
a. 5HT-1A
b. 5HT-1B
c. 5HT-1F
d. 5HT-3
OPERATION HARRI -P-90 (SESSION 24 – 19.8.07)
116. Cryoprecipitate contains all of the following except: [AIIMS-NOV-2007]
a. Factor VIII
b. Factor IX
c. Von Willebrand factor
d. Fibrinogen
OPERATION HARRI -P-664 (SESSION 29 – 23.9.07)
(Also in MKT)
198.
a. Pulmonary embolism
b. Tuberculosis
c. Bronchogenic Ca
d. ..
OPERATION HARRI -P-1562 (SESSION 20 – 29.7.07)
190. A female patient presents with diffuse alopecia to you. She had suffered from typhoid fever 4 months back. Most probable diagnosis is: [AIIMS-NOV-2007]
a. Androgenetic alopecia
b. Telogen effluvium
c. Anagen effluvium
d. Alopecia areata
OPERATION HARRI -P-TAB-299 (SESSION 26 – 2.9.07)
191. All of the following are causes of cicatrizing alopecia except: [AIIMS-NOV-2007]
a. Lichen planus
b. Discoid lupus erythematosus
c. Alopecia areata
d. Lupus vulgaris
OPERATION HARRI -P-297 (SESSION 26 – 2.9.07)
189. A 30 year old man presents with 6 month history of nasal discharge, facial pain and fever. On antibiotic therapy, fever subsided. After 1 month again had symptoms of mucopurulent discharge from the middle meatus and the mucosa of the meatus appeared congested and oedematous. Next best investigation would be: [AIIMS-NOV-2007]
a. FACIAL MRI
b. NCCT of the nose and para-nasal sinuses
c. Plain x-ray of the para-nasal sinuses
d. Inferior meatus puncture
OPERATION HARRI-P-188 (SESSION 25 – 25.8.07)
187. . A patient presents with Carcinoma of the larynx involving the left false cords, left arytenoids and the left aryepiglottic folds with bilateral mobile true cords. Treatment of choice is: [AIIMS-NOV-2007]
a. Vertical hemilaryngectomy
b. Horizontal hemilaryngectomy
c. Radiotherapy followed by chemotherapy
d. Total laryngectomy
OPERATION HARRI -P-505 (SESSION 28 – 16.9.07)
183. A 18 year old girl presents with amenorrhoea, weight loss and milky discharge from the breast. Most likely diagnosis is: [AIIMS-NOV-2007]
a. Anorexia nervosa
b. Occult carcinoma
c. Hypothyroidism
d. HIV
OPERATION HARRI -P-430 (SESSION 27 – 9.9.07)
178. Following is associated with maximum risk of invasive carcinoma of cervix : [AIIMS-NOV-2007]
a. Low grade squamous intraepithelial lesion
b. High grade squamous intraepithelial lesion
c. Squamous intraepithelial lesion associated with HPV-16
d. Squamous intraepithelial lesion associated with HIV
OPERATION HARRI -P-557 (SESSION 28 – 16.9.07)
(In consultants discussion-session-38-18-11-07)
91. Thiazides cause all except: [AIIMS-NOV-2007]
a. Hyperglycemia
b. Increased calcium excretion
c. Increased uric acid excretion
d. Useful in congestive heart failure
OPERATION HARRI -P-254,320-321 (SESSION 26 – 2.9.07)
(Also in consultants discussion)
94. Bisphosphonates are not used in: [AIIMS-NOV-2007]
a. Hypercalcemia
b. Osteoporosis
c. Cancer
d. Vitamin D intoxication
OPERATION HARRI P-562,567,1861 (SESSION 28, 9 – 16.9.07)
82. . In active chronic hepatitis B, all are seen except: [AIIMS-NOV-2007]
a.HbsAg
b.IgManti-HbcAg
c.HbeAg
d.Anti-HbsAg
Ans
OPERATION HARRI-P-1833 (SESSION 9 – 27.5.07)
126. Councilman bodies are seen in: [AIIMS-NOV-2007]
a. Alcoholic cirrhosis
b. Wilson’s disease
c. Acute viral hepatitis
d. ..
OPERATION HARRI-P-1828 (SESSION 9 – 27.5.07)
174. In osteomalacia, all are true except:[AIIMS Nov 2007]
a. Increased serum alkaline phosphatase
b. Increased serum calcium
c. Looser’s zones
d. Proximal myopathy
OPERATION HARRI-P-2248 (SESSION 4 – 29.4.07)
167. A child presents with history of respitory infections. His sweat chlorides levels are 36 and 41mEq/L on two different occasions. Which other test would you do to exclude the diagnosis of cystic fibrosis: [AIIMS Nov 2007]
a. Repeat sweat chloride measurements
b. Nasal electrode potential difference
c. Fat in stool for next 72 hours
d. DNA analysis for Δ508 mutation
OPERATION HARRI-P-1546 (SESSION 9 – 27.5.07)
168. A term infant has not passed meconium for 48 hours. He presents with distension of abdomen and emesis since one day. Next most appropriate investigation would be: [AIIMS Nov 2007]
a. Genetic testing for cystic fibrosis
b. Manometry
c. Lower bowel contrast enema
d. Oesophagoscopy
OPERATION HARRI -1545 (SESSION 9 – 27.5.07)
149. The best investigation is thromboembolism is: [AIIMS Nov 2007]
a. D-dimer levels
b. Multidetector CT angiography
c. Colour Doppler USG
d. Catheter angiography
OPERATION HARRIP-1490 (SESSION 21 – 5.8.07)
151. All are essential components of TOF except: [AIIMS Nov 2007]
a. Valvular pulmonic stenosis
b. Right ventricular hypertrophy
c. Infundibular stenosis
d. Aorta overriding
OPERATION HARRI-P-1389 (SESSION 23 – 12.8.07)
136. With CSF all are true except: [AIIMS Nov 2007]
a. Persistent leakage causes headache
b. Neutrophils are normally not present
c. pH is less than that of blood
d. Secreted by the arachnoid villi
OPERATION HARRI-P-A-11,1632 (SESSION 9 – 27.5.07)
138. Primary Pulmonary Hypertension IS CAUSED BY ALL EXCEPT [AIIMS Nov 2007]
a. Hyperventilation
b. Morbid obesity
c. Fenfluramine
d. High altitude
OPERATION HARRI-P-1406 (SESSION 21 – 5.8.07)
139. Cushing’s disease includes all except: [AIIMS Nov 2007]
a. Central obesity
b. Episodic hypertension
c. Easy bruisability
d. Glucose intolerance
OPERATION HARRI-2135 (SESSION 13 – 17.6.07)
140. Hypertension with hypokalemia is seen in all except: [AIIMS Nov 2007]
a. renal artery stenosis
b. End stage renal disease
c. Cushing’s disease
d. Primary hyperaldosteronism
OPERATION HARRI-P-258,2139,2131 (SESSION 13 – 17.6.07)
145. VHL syndrome includes all except: [AIIMS Nov 2007]
a. Endolymphatic sac tumours
b. Pheochromocytoma
c. Hemangioendotheliomas
d. Islet cell tumours
OPERATION HARRI – P - 2236,2453,2458 (SESSION 14 – 24.6.07, SESSION – 5 – 6.5.07)
44. In Lysosomal Storage Disorders, true is: [AIIMS Nov 2007]
a. The lysosomes are deficient in the enzyme hydrolase
b. There is a defect in the fusion od lysosomes and phagosomes
c. There is a defect in the lysosomal membrane
d. ..
OPERATION HARRI P-2318 (SESSION 15 – 1.7.07)
45. Vitamin K is required for: [AIIMS Nov 2007]
a. Carboxylation
b. Hydroxylation
c. ..
d. ..
OPERATION HARRI P-683 (SESSION 29 – 23.9.07)
54. Which vaccine should not be given to a child suffering from convulsions? [AIIMS Nov 2007]
a. Measles
b. BCG
c. DPT
d. OPV
OPERATION HARRI – P - 835 (SESSION 32 – 7.10.07)
(Also in consultant’s discussion)
56. Active method to detect undiagnosed cases in apparently healthy persons is: [AIIMS Nov 2007]
a. Screening
b. Surveillance
c. Case finding
d. Notification
OPERATION HARRI - 26 (SESSION 24 – 19.8.07)
(Also in consultant’s discussion)
65. Kala-azar, vector is: [AIIMS Nov 2007]
a. Flea
b. Tsetse fly
c. Sand fly
d. Mite
OPERATION HARRI-1233 (SESSION 36 – 28.10.07)
66. Scrub typhus is transmitted by: [AIIMS Nov 2007]
a. Reduvid bug
b. Trombiculid mite
c. Enteric pathogens
d. Cyclops
OPERATION HARRI – P – 1004 (SESSION 35 – 21.10.07)
72. . Regarding flourosis all are true except: [AIIMS Nov 2007]
a. Flourosis is the most common cause of dental caries in children
b Deposition of flurides in the skeletal system and muscles
c. Deflouridation is done by Nalgonda technique
d. Genu valgum
OPERATION HARRI – P .411 (SESSION 27 – 9.9.07)
73. All of the following are sources of Ω-3 PUFA except: [AIIMS Nov 2007]
a. Mustard oil
b. Groundnut oil
c. Corn oil
d. Fish oil
OPERATION HARRI – P-419,2296,2297 (SESSION 27 – 9.9.07, SESSION 15 – 1.7.07)
80. Prions consist of: [AIIMS Nov 2007]
a. DNA and RNA
b. DNA, RNA and proteins
c. RNA and proteins
d. Only proteins
Ans[d]
OPERATION HARRI -2495 (SESSION 4 – 29.4.07)
(Also in consultants discussion)
92. Regarding furosemide, true is: [AIIMS Nov 2007]
a. Given by parenteral route only
b. Used in pulmonary oedema
c. Acts at the PCT
d. .
OPERATION HARRI -1616 (SESSION 9 – 27.5.07)
88. True about fibrates is all except: [AIIMS Nov 2007]
a. (MOA)….PPARα….lipoprotein lipase…decreased LDL…
b. Absorped better on empty stomach and decreased on food intake
c. Side effects include rash, myalgia, impotence and many others
d. They are the drug of choice in type III hyperlipidemia and hypertriglyceridemia
OPERATION HARRI P-2297 (SESSION 15 – 1.7.07)
112. . In mitral valve prolapse, the histological finding is: [AIIMS Nov 2007]
a. Hyalinization of the valve
b. Fibrinoid necrosis
c. Myxomatous degeneration of the valve
d. ..
OPERATION HARRI-1395 (SESSION 23 – 12.8.07)
119. Most common site of subependymal giant cell astrocytomas is: [AIIMS Nov 2007]
a. Foramen of Monro
b. Temporal horn of the lateral ventricle
c. Trigone of the lateral ventricle
OPERATION HARRI P-2457 (SESSION 4 – 29.4.07)
121. Senile cardiac amyloidosis is due to defect in: [AIIMS Nov 2007]
a. β2 – microglobulin
b. Transthyretin
c. AANF
d. Pyrin
OPERATION HARRI P-2024 (SESSION 10 – 3.6.07)
104. All but one acts via GABA Aexcept: [AIIMS Nov 2007]
a. Thiopentone
b. Midazolam
c. Zolpidem
d. Promethazine
OPERATION HARRI P-2363 (SESSION 4 – 29.4.07)
144. Reye’s syndrome is ultrastructurally characterized by: [AIIMS Nov 2007]
a. Mitochondrial blebs and enlarged mitochondria
b. Depletion of glycogen
c. Dilatation of the endoplasmic reticulum
d. Perinuclear staining
OPERATION HARRI P-1871 (SESSION 9 – 27.5.07)
169. A 71/2 year old child presents with non-blanching rash over the extensor aspect of arm with swelling over knee. Urine analysis shows proteinurea + and hematuris +++. On kidney biopsy which finding will be most commonly seen: [AIIMS Nov 2007]
a. Fusion of podocytes
b. Acute tubular necrosis
c. Deposition of IgA
d. Thickened basement membrane
OPERATION HARRI P-1682 (SESSION 9 – 27.5.07)
131. A 23 year old male who is otherwise normal complains of mild pain in his right iliac fossa in a waveform pattern which increases during the night and he becomes exhausted and is admitted in the hospital. On examination there is mild hematuria. Urine examination reveals plenty of RBCs, 50WBCs/hpf. Urine pH is 5.5. Most likely diagnosis is: [AIIMS Nov 2007]
a. Glomerulonephritis
b. Ca-Urinary bladder
c. Ureteral calculus
d. ..
OPERATION HARRI P-1710 (SESSION 9 – 27.5.07)
137. . Not a feature of DKA is: [AIIMS Nov 2007]
a. Tachypnoea
b. Bradycardia
c. Abdominal pain
d. Dehydration
OPERATION HARRI P-2158-TAB (SESSION 14 – 17.6.07)
142. Marker for acute Hepatitis B is: [AIIMS Nov 2007]
a. HBV-DNA polymerase
b. IgG anti-HBc
c. Core antigen (HbcAg)
d. Anti-HbsAg
OPERATION HARRI P-1834-TAB (SESSION 9 – 27.5.07)
132. A patient presents with hyperparathyroidism. He has a family history of his siblings having pituitary involvement, thyroid nodules, pancreatic involvement, parathyroid hyperplasia and cutaneous angiofibromas. Most likely diagnosis: [AIIMS Nov 2007]
a. MEN 1
b. MEN 2A
c. MEN 2B
d. MEN 2C
OPERATION HARRI P-2231 (SESSION 14 – 24.6.07)
27. Sertoli cells in the testis have receptors for: [AIIMS Nov 2007]
a. FSH
b. LH
c. Inhibin
d. ..
OPERATION HARRI P-2188,2199 (SESSION 14 – 24.6.07)
(Also in consultants discussion)
179. According to the new WHO criteria, all are true in a normal person except: [AIIMS Nov 2007]
a. Sperm count > 20 million
b. Volume > 1 ml
c.
d. Aggressive forward motility in > 25 %
OPERATION HARRI 2188 (SESSION 14 – 24.6.07)
175. A 18 year old primigravida complained of decreased fetal movements. She delivered a baby weighing 2000gms at 30 weeks of gestation. The APGAR scores of the baby were 4 and 5 at 1 and 5 minutes respectively. The baby died in an hour. Post-mortem examination revealed multiple, peripheral, radially arranged cysts in the kidney. Most common associated finding in the baby would be: [AIIMS Nov 2007]
a. Holoprosencephaly
b. Hepatic cysts and hepatic fibrosis
c. Ureteral agenesis
d. Medullary sponge kidney
OPERATION HARRI P-1696 (SESSION 9 – 27.5.07)
15. Regarding genital development, true is: [AIIMS Nov 2007]
a. Y chromosome is associated with ovary development
b. Genital ridge starts developing at 5th week
c. Male genitals develop earlier than female genitals
d. Genital development is complete by 10th week
OPERATION HARRI P-2198,2214 (SESSION 14 – 24.6.07)
148. Most common site of spinal cord tumour is: [AIIMS Nov 2007]
a. Intradural extramedullary
b. Extradural
c. Intramedullary
d. All have equal distribution
185. Asherman’s syndrome is diagnosed by all except: [AIIMS Nov 2007]
a. HSG
b. Hysteroscopy
c. Endometrial culture
d. Saline infusion USG
OPERATION HARRI-2204 (SESSION 14 – 24.6.07)
